ESI (Emphysema Severity Index): Test for the assessment of emphysema in smokers, ex smokers and patients with COPD
The ESI-test is performed calculating a quantitative score (0-10) reflecting the severity of emphysema. The calculator is derived by a biomechanic mathematical model developed after 10 years of research and experiments.
ESI has been validated in a large population of smokers, ex smokers and subjects with COPD.
ESI is now available for:
- Emphysema assessment by spirometry in smokers, ex-smokers, patients with COPD
- Application on prospective wide-scale clinical trials
- Post-hoc analyses of previous randomized pharmacologic clinical trials to evaluate the effects of emphysema severity on the outcome
- Scientific partnerships and publications
- Integration on portable devices and spirometers
- Integration of ESI in clinical records software
- Batch analysis of large datasets
The analysis is based uniquely on data derived by standard spirometry without any standardization or normalization (i.e. % pred. or LLN, z-scores, etc…, DLco is not requested.)
Contact us to integrate ESI in your projects:
Emphysema in smokers and COPD
According to WHO (World Health Organization): “Chronic Obstructive Pulmonary Disease (COPD) is not one single disease but an umbrella term used to describe chronic lung diseases that cause airflow obstruction.
The more familiar terms ‘chronic bronchitis‘ and ‘emphysema‘ are no longer used, but are now included within the COPD diagnosis.” According to the recent estimates, currently 64 million people have COPD and 3 million people died of COPD. WHO predicts that COPD will become the third leading cause of death worldwide by 2030.
Chronic obstructive pulmonary disease (COPD) is a complex condition with a wide spectrum of clinical presentations and pathological features unified under the spirometric definition of airflow obstruction. Airway narrowing and parenchymal destruction are recognized as the mechanisms responsible for airflow obstruction in COPD, but they cannot be distinguished by standard spirometry indexes such as FEV1 (%pred) or FEV1/FVC.